Category Longevity

Japanese Miniatures: Hara Hachi Bu

In the west we start a meal by saying  “Have a nice dinner” or “Bon appetite”. We refer to the quality of the eating experience but never to the quantity. In contrast, on the Japansese island of Okinawa, they say “Hara Hachi Bu” which means “Eat until you’re only 80% full”. It wishes us to […]

FOXO3a

Recent studies have identified the FOXO3a (Forkhead Box 3a) transcription gene as an important regulator of morphological scaling. It’s a key regulatory gene in a nutrient- and energy-sensing biological pathway (insulin/IGF-1 signalling pathway),that throughout our evolution was conserved from yeast to humans. FOXO3a anticipates food scarcity by slight alterations to its functionality with resultant phenotypic changes including […]