Category: Epigenetics

Dino/Bird Maker Space

March 25, 2024 By arne hendriks Off

Birds evolved through a unique phase of sustained miniaturisation in theropod dinosaurs. They didn’t just shrink but continued to do so over long periods of time. Therefor we can conclude that long before their small decendents developed the ability to fly, smallness must already have…

The Tall Dutch

April 9, 2015 By arne hendriks 0

The Dutch are the tallest people in the world: its women stand almost 1.71 metres (5.6 feet) tall, and its men 1.84 metres. But how the Dutch became the world’s tallest people is still debated. Now a Dutch scientist, Gert Stulp, of the London School…

2000+ Genetic Factors

December 9, 2014 By arne hendriks 1

Since 2007 researchers of the Genetic Investigation of Anthropometric Traits (GIANT) consortium are quickly uncovering the polygenic traits that influence human height.  Recently they analysed data from the genomes of another 253,288 subjects and were able to identify 697 gene variants, the pieces of DNA that…

Catch-Up Growth

July 8, 2014 By arne hendriks 2

Catch-up growth is the accelerated growth of an organism following a period of slowed development. Such slowing down is most often the result of environmental influences such as food scarcity, sudden changes in temperature, or other environmental stress factors. After the situation is normalised, growth…

FOXO3a

June 20, 2014 By arne hendriks 0

Recent studies have identified the FOXO3a (Forkhead Box 3a) transcription gene as an important regulator of morphological scaling. It’s a key regulatory gene in a nutrient- and energy-sensing biological pathway (insulin/IGF-1 signalling pathway),that throughout our evolution was conserved from yeast to humans. FOXO3a anticipates food scarcity…

Microbial Temper Tantrums

March 22, 2014 By arne hendriks 0

In stressful conditions, cells must prevent the initiation of replication and shift their priorities to protective functions. In other words: they must stop division and growth. Experiments in bacteria at the University of Massachusetts Amherst have uncovered the mechanism that translates stress into blocked cell growth.…

Pit-1

January 13, 2014 By arne hendriks 0

Human height is the result of how genetic height potential is turned into reality by circumstance. From the first whispers of life in the womb, the DNA in the nuclei of the embryo’s cells ‘monitors’ what situation to expect at birth, and develops the body…